An immune evasion mechanism with IgG4 playing an essential role in cancer and implication for immunotherapy
Background Recent impressive advances in cancer immunotherapy have been largely derived from cellular immunity.The role of humoral immunity in carcinogenesis has been less understood.Based on our previous observations 275/60r15 mickey thompson we hypothesize that an immunoglobulin subtype IgG4 plays an essential role in cancer immune evasion.Method