AN IMMUNE EVASION MECHANISM WITH IGG4 PLAYING AN ESSENTIAL ROLE IN CANCER AND IMPLICATION FOR IMMUNOTHERAPY


Interacting Temperature, Nutrients and Zooplankton Grazing Control Phytoplankton Size-Abundance Relationships in Eight Swiss Lakes

Biomass distribution among size classes follows a power law where the Log-abundance of taxa scales to Log-size with a slope that responds to environmental abiotic and biotic conditions.The interactions between ecological mechanisms controlling the slope of locally realized size-abundance relationships (SAR) are however not well understood.Here we t

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On the Fundamental Possibility of a Supersonic Civil Aircraft to Comply with ICAO Noise Requirements Using Existing Technologies

Compliance with environmental protection regulations, in particular, community noise requirements, constitutes one of the major obstacles for designing future supersonic civil aircraft.Although there are several noise sources that contribute to the total noise level of supersonic aircraft, it is the turbulent jet that appears most problematic; jet

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A Novel Myosin Essential Light Chain Mutation Causes Hypertrophic Cardiomyopathy with Late Onset and Low Expressivity

Hypertrophic cardiomyopathy (HCM) is caused by mutations in genes encoding sarcomere proteins.Mutations in MYL3, encoding the essential light chain of myosin, are rare and have been associated with sudden death.Both recessive and dominant patterns of inheritance have been suggested.We studied a large family with a 38-year-old asymptomatic HCM-affec

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